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副教授

张语迟

2017年01月13日 18:30  点击:[]

教师个人简介

姓名

张语迟

性别

生年月

1984.03

职务(职称)

副教授

学位

理学博士

E-mail

zhangyuchi2001@163.com

办公电话

0431-86168379

办公地址

文科实验楼611室

专业

分析化学

研究方向

天然药物化学

荣誉称号

吉林省首批高校科研春苗人才

主讲课程

综合和设计实验;商品理化检验

学习经历

2010.092014.06  东北师范大学,澳门新葡亰所有官网,理学博士

2005.062008.06  长春中医药大学,药学院,医学硕士

2001.092005.06  长春中医药大学,药学院,理学学士

工作经历

2016.01至   今    长春师范大学,中心实验室,副教授

2011.012016.01    长春师范大学,中心实验室,讲师

2008.062011.01    长春师范大学,中心实验室,助教

获奖情况

1. 张语迟,刘春明,齐艳娟,李赛男,王晶,李东平,天然产物的快速分离提取及结构解析研究,吉林省自然科学学术成果奖,一等奖,2014年。

2. 张语迟,刘春明,张正坤,吴桂梅,李赛男,王晶。罗布麻叶有效成分的分离提取及鉴定分析,吉林省自然科学学术成果奖,二等奖,2011年。

3. 刘春明,张语迟,刘舒,郑梅竹,王晶,刘志强,时东方,皮子凤。常用中药材中治疗糖尿病等症的活性成分分离筛选及结构表征研究,吉林省科技进步奖,二等奖,2014年。

4. 刘春明,张语迟,郑梅竹,郭飞军,时东方。传统中药罗布麻抗抑郁有效成分的分离提取及新药开发研究,吉林省科技进步奖,二等奖,2012年。

学术成果

专利

1. 刘春明,张语迟,白云鹏,齐艳娟,吴桂梅,一种罗布麻叶提取物的制备方法。专利号:ZL 200910067196.5.

2. 宋凤瑞,张语迟,刘志强,王淑敏,刘淑莹,一种人参保健品冲剂的制备方法。专利号: ZL 200810051162.

3. 宋凤瑞,张语迟,王淑敏,刘志强,刘淑莹, 一种增加人参总皂苷提取物中稀有皂苷含量的方法, 专利号:   200810050535

科研项目

1、国家自然科学基金青年基金项目,31500279、利用数学模型辅助筛选三七及变种植物中抗帕金森病有效成分、2016/01-2018.1222万元、在研、主持。

2、吉林省科技发展计划青年基金项目,20150520140JH、五加科代表性植物抗阿尔茨海默病有效成分的分离提取及活性评价研究、2015/01-2017/126万元、在研、主持。

3、吉林省教育厅“十二五”科学技术研究项目,吉教科合字第[2013]253、中药人参、三七和西洋参中稀有皂苷的分离提取及抗帕金森病的活性评价研究、2013/01-2014/122万元、已结题、主持。

4、国家自然科学基金面上项目,31670358、药用植物异黄酮类成分抗缺血性脑卒中的活性筛选及作用机制研究、2017/01-2020.1263万元、在研、参加(第三位)。

5、国家自然科学基金面上项目,31370374、人参属植物抗阿尔茨海默病的活性成分筛选方法及作用机制研究、2014/01-2017.1282万元、在研、参加(第二位)。

6、吉林省科技发展计划重点项目,20160101336JC、异黄酮类化合物的分离提取及抗癫痫病活性评价研究(探索)、2016/01-2018/1210万元、在研、参加(第二位)。

7、吉林省科技发展计划团队项目,20130521013JH、治疗神经退行性疾病活性成分分离纯化及筛选创新团队、2013/01-2015/1215万元、在研、参加(第二位)。

8、国家自然科学基金面上项目,31170326,药用植物抗帕金森病的活性成分筛选及作用机制的研究、2012/01-2015/1268万元、在研、参加(第二位)。

9、吉林省科技发展计划重点项目,20110928、常用中药材中治疗糖尿病等症的活性成分筛选及物质资源库的建立、2011/01-2013/1225万元、已结题、参加(第二位)。

10、国家自然科学基金面上项目,30970299、药用植物罗布麻抗抑郁成分的分离、活性评价及作用机制的研究、2010/01-2012/1233万元、已结题、参加(第二位)。

11、吉林省科技发展计划重点项目,20090936、传统中药罗布麻抗抑郁有效成分的分离提取及新药开发研究、2009/01-2011/1029万元、已结题、参加(第二位)。

学术成果

科研论文

1.   Yuchi Zhang, Jianxu Zhang, Chunming Liu, Min Yu, Sainan Li.   Extraction, isolation, and aromatase inhibitory evaluation of low-polar   ginsenosides from Panax ginseng leaves [J]. Journal of Chromatography A,   2017, 1483: 20–29. (SCI, IF=4.258, Top期刊)

2.   Yuchi Zhang, Jingying Xu, Chunming Liu, Sainan Li. Screening of   neuraminidase inhibitors from the leaves of Syringa velutina Kom. via   compound fractionation and in vitro activity evaluation [J]. Analytical   Methods, 2017, 9, 500–510.

3.   Yuchi Zhang, Chong Shi, Chunming Liu, Min Yu, Yanjuan Qi,   Sainan Li. Saponins from Panax bipinnatifidus Seem.: New strategy of   extraction, isolation, and evaluation of tyrosinase inhibitory activity based   on mathematical calculations [J]. Journal of Chromatography B, 2016,   1039, 79–87

4.   Yuchi Zhang, Chunming Liu, Yanjuan Qi, Sainan Li, Yan Pan,   Yuchun Li. Circulating ultrasound-assisted extraction, countercurrent   chromatography, and liquid chromatography for the simultaneous extraction,   isolation, and analysis of the constituents of Uncaria tomentosa [J]. Journal   of Chromatography A, 2015, 1388: 36–42. (SCI, IF=4.258, Top期刊)

5.   Yuchi Zhang, Chunming Liu, Jing Li, Yanjuan Qi, Yuchun Li, Sainan   Li. Development of “ultrasound-assisted dynamic extraction” and its   combination with CCC and CPC for simultaneous extraction and isolation of   phytochemicals [J]. Ultrasonics Sonochemistry, 2015, 26: 111–118 (SCI,   IF=3.816, Top期刊)

6.   Yuchi Zhang, Chunming Liu, Yanjuan Qi, Yuchun Li, Sainan Li.   Dynamic ultrasonic-assisted extraction coupled with paralleled   counter-current chromatography for continuous extraction and online isolation   of xanthenones from Garcinia mangostana [J]. Separation and Purification Technology,   2015, 144: 215–222. (SCI, IF=3.065)

7.   Yuchi Zhang, Chunming Liu, Yan Pan, Yanjuan Qi, Yuchun Li,   Sainan Li, Yueqi Wang. Ultrasound assisted dynamic extraction coupled with   parallel countercurrent chromatography for simultaneous extraction, purification,   and isolation of phytochemicals: Application to isoflavones from red clover   [J]. Analytical and Bioanalytical Chemistry, 2015, 407:4597–4606 (SCI, IF=3.578)

8.   Yuchi Zhang, Chunming Liu, Yanjuan Qi, Yuchun Li, Sainan Li.   Development of circulating ultrasound-assisted online extraction coupled to   CCC and CPC for simultaneous extraction and isolation of phytochemicals:   Application to Ligusticum chuanxiong Hort [J]. Industrial &   Engineering Chemistry Research, 2015, 54, 3009−3017 (SCI, IF=2.235, Top期刊)

9.   Yuchi Zhang, Chunming Liu, Yanjuan Qi, Yuchun Li, Sainan Li,   Yuqi Wang, Junqi Ren, Ying Tang. Efficient Combination of Circulating   Ultrasound-assisted Extraction and Centrifugal Partition Chromatography for   Extraction and Online Separation of Chemical Constituents from Stellera   chamaejasme L. [J]. Phytochemical Analysis, 2015, 26, 301–309 (SCI,   IF=2.450)

10.   Yuchi Zhang, Liping Guo, Chunming Liu, Zoao Fu, Lei Cong, Yanjuan Qi,   Dongping Li, Sainan Li. Wang Jing. Pressurized liquid extraction coupled with   countercurrent chromatography for systematic isolation of chemical   constituents by preprogrammed automatic control [J]. Journal of   Chromatography B, 2013, 935: 16–25. (SCI, IF=2.888)

学术成果

11.   Yuchi Zhang, Liping Guo, Chunming Liu, Yanjuan Qi, Dongping Li,   Sainan Li. Combination of pressurized liquid extraction with countercurrent   chromatography for systematical isolation of ginsenosides from Panax   ginseng[J]. Separation and Purification Technology, 2013, 116:   240–247. (SCI, IF=2.921)

12.Yuchi   Zhang, Chunmin Liu, Yanjuan Qi, Sainan Li, Jing Wang. Application of   accelerated solvent extraction coupled with counter-current chromatography to   extraction and online isolation of saponins with a broad range of polarity   from Panax notoginseng [J]. Separation and Purification Technology,   2013, 106: 82–89. (SCI, IF=2.921)

13.Yuchi Zhang,   Chunming Liu, Yanjuan Qi, Guimei Wu, Sainan Li. Fast Differentiation of Apocynum   venetum with Related Species by UPLC/MS and UPLC/SPE/NMR [J]. Medicinal   Chemistry Research, 2012, 21:1077–1083. (SCI, IF=1.612)

14. Yuchi   Zhang, Chunming Liu, Yanjuan Qi, Zhengkun Zhang. Comparison of the   constituents of Apocynum venetum and acidified Apocynum venetum   by liquid chromatography–UV diode array detection–electrospray ionisation   mass spectrometry [J]. Medicinal Chemistry Research, 2012, 21:   1684–1691. (SCI, IF=1.612)

15.ZHANG   Yu-chi, PI Zi-feng, LIU Chun-ming, SONG Feng-rui, LIU Zhi-qiang and   LIU Shu-ying. Analysis of Low-polar Ginsenosides in Steamed Panax Ginseng   at High-temperature by HPLC-ESI-MS/MS [J]. Chemistry Research in Chinese   Universities, 2012, 28(1), 31–36. (SCI, IF=0.379)

16.   Yuchi   Zhang,   Chunming Liu, Min Yu, Zhengkun Zhang, Yanjuan Qi, Jing Wang, Guimei Wu,   Sainan Li, Jing Yu, Yang Hu. Application   of accelerated solvent extraction coupled with high–performance   counter–current chromatography to extraction and online isolation of chemical   constituents from Hypericum perforatum L. Journal of Chromatography   A, 2011, 1218: 2827–2834. (SCI, IF=4.531, Top期刊)

17.   Yuchi Zhang, Chunming Liu, Zhengkun Zhang, Jing Wang, Guimei   Wu, Sainan Li. Comprehensive separation and identification of chemical   constituents from Apocynum venetum leaves by high-performance   counter-current chromatography and high performance liquid chromatography   coupled with mass spectrometry [J]. Journal of  Chromatography B,   2010, 878: 3149–3155. (SCI, IF=2.888)

18.   Yuchi Zhang, Chunming Liu, Zhengkun Zhang, Yanjuan Qi, Guimei   Wu, Sainan Li. Solvent gradient elution for comprehensive separation of constituents   with wide range of polarity in Apocynum venetum leaves by high-speed   counter-current chromatography[J]. Journal of Separation Science.   2010, 33: 2743–2748. (SCI, IF=2.733)

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